Foundation for Advancement in Cancer Therapy

Non-Toxic Biological Approaches to the Theories, Treatments and Prevention of Cancer

The Foundation for Advancement in Cancer Therapy (FACT) founded in 1971, is a federally approved 501(c)(3) organization. All proceeds from donations, sale of the DVD, and the books Triumph Over Cancer, Rethinking Cancer, and Detoxification are tax deductible. Your contributions help to fund FACT's educational efforts.

More About FACT

Visit the new
FACT Product Guide

Flouridation & its Consequences
By Richard A. Passwater, Ph.D.


Letter to Eastern Shore Times, Ocean City, Maryland

Dear Editor

The Times recently presented pro and con statements about the suggestion to fluoridate Ocean City's water supply. The article ended with an opinion from the proponent contending "there is no safety issue which needs determination." This is a serious issue of public safety, and the public should know the facts.

There are several areas of concern including kidney, thyroid, liver and spleen damage as well as increased cancer death rate, birth defects and allergies.

Consider the following from the enclosed 1978 article published in the scientific journal Bios by Dr. K. Hansen of the Department of Pathology at the College of Medicine and Dentistry of New Jersey.

"There has been speculation that fluoride replaces iodine in the body. It is claimed that the number of thyroid cancers in San Francisco has gone up five times since the introduction of fluoridation (Lough et al., 1975). According to McLaren (1976), fluoride appears to be actively concentrated by thyroid cells.

"The purpose of the research described herein was to study the histological effects of various concentrations of fluoridated water on the thyroid, spleen, liver, kidney, heart, stomach, intestine, and bone of female mice. .

"Fluoride in the diet of female CSE mice at levels as low as 1 ppm causes pathological changes in kidney, thyroid, liver and spleen. This fluoride concentration approximates that added to public water supplies."

Thus we have an uncontested, current, previewed scientific confirmation by a qualified expert of the damage caused by 1 ppm fluoridated water to the kidney, thyroid, liver, and spleen.

Earlier, studies had shown that kidney patients had accelerated damage from fluoridated water (Journal of the American Medical Association 222 (13) 783-5 (1972); Marier (1977) and Mernagh et al. (1977) from attachment 7 of my letter to Mayor Kelley and the City Council).

Drs. Summers and Keitzer of the Akron General Medical Center reported a significant increase in calcium-based kidney stones after fluoridation of Akron's water supply.

Drs. Summers and Keitzer of the Akron General Medical Center reported a significant increase in calcium-based kidney stones after fluoridation of Akron's water supply (Ohio State Medical Journal, Jan. 1975). In 1961, Dr. Taylor of the University of Texas reported fluoride caused kidney stones in mice, a condition not encountered before in his mouse colony.

THYROID

How many Ocean City residents have either hypothyroidism or hyperthyroidism? As mentioned earlier, Dr. Hansen has shown that fluoridated water causes thyroid damage. Drs. Day (1972) and Teotia (1975) have shown that fluoridated water increases the occurrence of goiter. Dr. Crawford (1972) has reported that fluoride in drinking water blocks iodine absorption . . . a proportion of the population may come to have sub-optimal iodine intake. The effects might be subtle and slow to develop, and would certainly not be picked up by the crude screening used at present (Ref: see attachment 7). Dr. Bobek observed that fluoride caused a decrease in blood thyroxine which alters thyroid hormones.

BONE

High fluoride content of drinking water caused bone abnormalities in 251 tanzanian children including deformed feet, barrel-shaped chests and leg abnormalities (Christie, Radiology, 1980). Dr. Christie commented "Excessive fluoride ingestion in pregnant women may possibly poison and alter enzyme and hormonal systems in the fetus, causing disturbances in bone formation and mineralization." The children had incapacitating pains never known in previous generations. Researchers used to believe it took 20 to 30 years of drinking water with a high fluoride content to produce osteofluorosis. Until recently, there had been only a few reports of these skeletal changes in children."

Earlier bone deformations had been reported to be extensive in a region in India having 3.5 ppm of fluoride in the drinking water (Krishnamachar, Lancet, 1973). In a special report on osteoporosis in the January 1980 Consultant, Dr. G. Gordon stressed "fluoride causes fluorosis with pain, poor quality bone, fractures, ectopic calcification, and neurologic disturbances . . . Fluoride combines with hydrochloric acid, a substance that frequently produces peptic ulcers and hematemesis."

Yet fluoride proponents try to tell us that it's good for the bones! The editorial in the February 1980 issue of the Journal of the American Medical Association stressed that in patients with osteoporosis treated with fluoride, there is a high prevalence of side effects and no reduction in fracture frequency. The major side effects occurring in 42 percent of such patients taking fluoride include synovitis (painful joints), painful plantar fascial syndrome, recurrent vomiting and anemia (Specht, Western Journal of Medicine, October 1980). Other side effects include gastric ulcer, joint stiffness, hair loss, neurological disease, cerebral demyelination, Parkinson's disease, peripheral neuritis, and retinal macular degeneration (Riggs, JAMA, Feb. 1980).

In 1975, Dr. Inkovaara found substantially more fractures in a fluoride treated group (370 versus only 32 in the equal non-fluoride group) (Brit. Med. J.). It seems that fluoride can harden bone, but it makes bone (and teeth) more brittle.

The level of fluoride in fluoridated water (1 ppm) is sufficient to cause the mottling of teeth, which is an indication of bone and tooth damage.

MOTTLED TEETH

After fluoridating Newburgh, NY for 10 years, 18 percent of the children had mottled teeth compared to 1 percent in Kingston (Asst, J. Amer. Dental Assoc., 1956). After fluoridating Grand Rapids, Mich., 19 percent of white children and 40 percent of black children had mottled teeth (Russell, J. Amer. Dental Assoc., 1962). In Casa Grande, Ariz., the level was 86 percent (U.S. Pub. H. Rpt. 68).

CANCER

The link between fluoridation and cancer has been established by several investigators. The best way of summarizing the evidence is to refer
to the evidence given in open court against the Director of Public Health State of Illinois, et al. over a period of ten weeks during this past spring. Drs. Dean Burk and John Hiamouyiannis presented the findings of one of the largest and most sophisticated epidemiological studies in modern science, covering the fluoridation-cancer experience of 18 million Americans over 30 years. There were controls for known and unknown variables, including geographic, demographic, environmental, and dietary factors; consideration of periods before and after the introduction of fluoridation in the experimental cities; double-blind design to control for bias; an objective and manageable index of time trends studied; together with elaborate adjustments for age, race, and sex by direct and indirect methods. A significant increase in cancer deaths in humans was associated with the introduction' of fluoridation. The data show that 10,000 to 30,000 Americans die of cancer each year due to the effects of fluoridation.

A principle of scientific logic, called "decam's Razor," dictates that this evidence is considered as fact unless someone can conduct a similar study that holds up to scientific criticism which shows otherwise. The essence of logic is that given a strong association between observed phenomena, one should assign the first, most obvious and natural explanation as to the cause, and this must be taken as fact, unless and until the contrary be demonstrated. To, upset such a causal inference, it is not enough to postulate other possibilities; any alternative thesis must be proven as fact, or at least to be more plausible or probable, otherwise the first-assigned cause stands.

The Burk-Yiamouyiannis evidence withstood all challenge during the trial and no counter evidence could be proposed by experts summoned by the defense. This surely dictates that a community should ' not fluoridate unless new studies can determine the present studies are in error.

We can see suggestions as to the truth of the evidence here in Maryland. It may be a coincidence, but Maryland ranks in the top four states in percentage of population drinking fluoridated water and ranks number one in cancer death rate. Baltimore, which has been fluoridated since 1952 is the most cancer-prone
city for white males, and Washington, D.C., also fluoridated in 1952, is first in cancer death rate for black males. Somerset County which has drinking water contaminated with a high fluoride level has a cancer death rate of 316 per 100,000 population compared to the state rate of 184 per 100,000. Dorchester County, which has a high percentage of the population drinking water contaminated with a high fluoride level has the second highest rate, 285 per 100,000 population.

The statement that "link between fluoridation and cancer has not been proven" is particularly alarming. First of all, the legal burden lies on those who are proposing to contaminate the public water supply to prove safety. The accepted procedure for other drugs' (fluoridation is mass medication) and food additives is to conduct a series of tests in two or more animal species. Unfortunately, Dr. Al Taylor of Texas A & M has shown that fluoride does indeed promote cancer in animals.

Secondly, everyone has the freedom to choose whether or not they will ingest a cancer-causing chemical or even only a "suspected" cancer causing chemical. Some people are "not impressed" with t,he evidence linking cigarette smoking with lung cancer. Others are. But we don't force everyone in the community to smoke. Fluoridation forces everyone that drinks or eats food prepared in that community to ingest fluoride.

ALLERGIES

In the Illinois trial, Dr. G. Walbott testified that allergies (intolerance) to fluoride in drinking water is a fairly common phenomenon. Typical signs are musculoskeletal symptoms including pains in joints, muscles and chest, muscle weakness and twitching, and backache; neurological symptoms, including headache, numbness in hands and feet, dizziness, visual disturbances, ringing in the ears, and convulsions; stomach symptoms, including pain, nausea, vomiting, and bloated abdomen; bowel symptoms, including pain and diarrhea; and a number of other symptoms including hives. Fluoridated water can bring misery to the one-to-ten percent of any population allergic to fluoride.

BIRTH DEFECTS

In 1976, Professor A.H. Mohammed of the University of Missouri reported "As little as 1 ppm of fluoride in drinking water can produce permanent genetic damage in mice. The chromosomal damage and breakdown observed in the study is believed to be the direct result of fluoride acting on the DNA." Dr. Mohammed's
findings have withstood scientific cross-examination in court challenges to fluoridation. Mongolism (Down's Syndrome) is a birth defect that has two separate aetiological processes one affecting younger mothers and independent of maternal age and the other, a more frequent phenomenon, affecting older mothers (Stoller, 1963). Dr. Rapaport has shown in three studies (1956, 1959, 1961) that a parallelism has been observed between the incidence of mongolism and the fluoride content of drinking water. Dr. W. Berry confirmed this in a Texas study. A 1974 study in Massachusetts by Dr. Needleman claimed not to find an elevated risk for mongolism, but Dr. J.R. Lee stated that the data do suggest that fluoride causes an elevation of mongolism. While the mongolism question is still a question, the genetic damage is established.

NERVE DAMAGE

Fluoride impairs the central nervous system. Fluoride affects metabolism in nerve cells and disturbs receptor function and the transmission of nerve impulses (Gabovich and Ovrutsky, 1977). The Executive Director of the Feingold Association of New York for Hyperactive Children stated that fluoride cannot be tolerated by hyperactive children because it has a severe adverse reaction upon their nervous systems (Gelardi, 1976).

ENZYME DAMAGE

Four Nobel prize winners Euler, Warburg, Theorell, and Summer working independently, have shown that a number of enzymes of great importance are destroyed by fluoride at concentrations between 0.2 and 1 ppm.

The enzymes catalase and superoxide dismutase help protect against cancer, but they are destroyed by fluoride. Dr. Holman pointed out in 1961 that "many observations have suggested that agents which decrease the catalase of cells may predispose to tumor formation. Since fluoride can inhibit catalase and since it is a cumulative poison, the danger of increasing the cancer-inducing potential in humans must be considered." Dr. Steyn commented in 1964 that catalase destruction is known to be associated with mutagenic and carcinogenic processes. The relationship of fluoridation to cancer was discussed earlier.

All the chemical reactions necessary to the life and function of the body depend on enzymes.

Continuous depression of enzyme activity by fluorides produces alterations of function and symptoms of disease.

TOXICITY

The danger of fluoride is not so much the immediate threat of poisoning, as it is the insidious cumulative effect of slow damage to the body. Yet fluoride is a poison several times more toxic than arsenic. Several cases have been documented wherein people have died solely from the direct toxic effect of fluoride in drinking water. Others have died from swallowing fluoride gels or mistakes in fluoridating drinking water. Last year in Berlin, while a State Public Health Official was guaranteeing the audience at the Berlin debate that such accidents can't happen because of safeguards, an Annapolis man lay dead at that very moment because of a fluoride "spill".

A list of reports that are often quoted as demonstrating safety is enclosed. The mistakes made in each report is discussed. The best way to illustrate the lack of adequate safety testing is to quote from Congressional proceedings.

DISREGARD FOR SAFETY

The following excerpts from the House Select Committee to Investigate the Use of Chemicals in Food chaired by Congressman Delaney illuminate the lack of safety concern by fluoridation proponents.

From Page 1632 of the Record:

Dr. Miller (physician and Congressman): "There are answers you have not found to questions relative to the effects of fluoride upon other than dental functions of the body. Do you think that the public interest is best served by a more cautious attitude about the use of fluoride?"

Dr. Arnold (Public Health Service): "No, sir. I think the public interest is best served by having the public start putting fluoride in the water supply today."

Dr. Miller: "Since the studies have-not been completed on what happens to children with damaged kidneys and nothing has been done on adults, how can you say positively that there are no deleterious effects? Do you know of any experiments that have been carried on by the Public Health Service or the American Dental Association or the American Medical Association in relation to what happens to old people, people that may have chronic disease, diseased kidneys the effects of fluoride on that group?"

Dr. Ast: of the New York State Health Department, Director of the Newburgh fluoridation project, did not know of any such experiments. Page 1759:

Dr. Miller: "No experiments have been carried on as to the effects on older people or even pregnant women?"

Dr. Ast: "Yes, that is correct."

Dr. Miller: "And there might be some deleterious effects to people with damaged kidneys or pregnant women or those with chronic diseases, in the older group?"

Dr. Ast: "If that were qualified by the statement that the likelihood is very remote, and that is based on the endorsement by such organizati6ns as the American Medical Association, the National Research Council, the American Public Health Association, and others."

Dr. Miller: "These organizations have made no experiments, no examinations as to the effects by their own testimony."

Dr. Ast: "Yes."

Dr. Miller: "So why should they endorse?"

Dr. Heyroth (representing the National Research Council): "I still feel that we need investigations of the ability of abnormal kidneys to excrete fluorides." . . . "We are dealing there with abnormal people and we can't make general regulations that would apply. We don't prohibit sugar because some people can't take it because of diabetes."

(Note: The important issue is that they are not forced to eat sugar against their wishes.)

Mr. Kleinfeld (Counsel to the Committee): "Is it not true, doctor, that you can live without sugar but you have got to have water?"

Dr. Heyroth: "That is right. The advice would be to drink some water that is free from fluoride, which could be done."

Mr. Kleinfeld: "He would have to get his water privately?"

Dr. Heyroth: "He would if it can be established that he is going to be sick for the rest of his life."

Chairman Delaney: "Sodium fluoride is very toxic?

Dr. Ast: "Yes."

Congressman Delaney: "If we use it daily in all our cooking and for drinking purposes if we do that day in and day out for years could that possibly have an effect?"

Dr. Ast: "I don't think so, but I can't answer categorically it will not."

In 1975, Congressman Delaney demanded that fluoridation be halted. (Dec. 11, 1975 Congressional Record).

Frank Bull, DDS, Wisconsin Dental Health Director, served as chief coach of the Fourth Annual Conference of State Dental Health Directors with the Public Health Service to nationalize the fluoridation bandwagon. The following quotations from Dr. Bull suggest both the attitude and the logistics:

"What are some of the objections? Isn't fluoride the thing that causes mottled enamel or fluorosis? Now we tell them this: that at 1 ppm dental fluorosis (mottled teeth) brings about the most beautiful looking teeth anyone ever had. And we show them some pictures. We don't try to say that there's no such thing as fluorosis, even at 1 ppm, which we are recommending. But you have got to have an answer. Maybe you have a better one.

"Now in regard to toxicity. This toxicity question is a difficult one. I can't give you the answer to that one. So when you get the answer on the question of toxicity please write me at once, because I would like to know.

"Don't let them get you on the defensive. . . When they say yes, you say no. You just say we know it's safe . . . and pass on. Do we want to promote this thing or do we argue about it?"

SAFETY CLAIMED

Dr. Prival of the Center for Science in the Public Interest points out:

"Those who claim that fluorides have no significant adverse effects on health can point to only two such studies relating to non-fatal, non-skeletal conditions. One, the Bartlett-Cameron (Texas) study, was so inadequate in terms of the number of people investigated as to be useless in determining the effects fluoride might have on a small fraction of the population. The other, the Newburgh-Kingston (New York) study, examined only children (Note: children who were ill recently were excluded; they were the ones who should have been studied) and was terminated after only ten years of artificial fluoridation of Newburgh's water. Manjf diseases develop over periods of 20 or 30 years or longer. The Newburgh-Kingston study is thus of no value in assessing the effects of long-term use of fluoridated water or effects on adults. . .

"It is the responsibility of those who now have the powers to decide or recommend action on such matters (as fluoridation) to be far more responsive to the public demand for a safer environment. This responsibility falls heavily on those who recommend universal fluoride ingestion for the prevention of dental caries but who refuse to continue research on the health effects of this measure."

In the town of Bartlett, Texas, just 116 persons were examined. This is the "natural fluoride" town, with 8 ppm fluoride in the drinking water. In Cameron, Texas, the control or reference town, with a population of over 5000, only 118 persons were studied.

Cameron is called a "non-fluoride" town but has 0.5 ppm in water. Both Bartlett and Cameron are situated in the Texas high-fluoride area, with more than average concentrations in the soil and air; which makes them a poor choice for the experiment. The project is termed "A Ten Year Study" because ten years elapsed between the two examinations. During this interval, twenty-two subjects left Bartlett, twenty-five left Cameron. In the first place, only eleven of the persons who were studied in Bartlett had lived there all their lives and consequently used the water consistently; only thirty persons in the study had always lived in Cameron.

The study shows that the death rate in the "fluoride" town Bartlett was three and a half times that of the "non-fluoride" town of Cameron. Nonetheless the researchers concluded that there were no significant differences.

The National Research Council remarks about this study in their Publication 294: "The greater incidence in the high fluoride group (Bartlett) of a certain brittleness and blotching of fingernails, of hypertrophic changes in the spine and the pelvis, and of lenticular opacities of the eyes (cataracts) requires further investigation. Also, there are more full mouth extractions in Bartlett (fluoride town) than in Cameron (non-fluoride town). (Note: fluoride makes teeth harder and slightly more resistent to acid, but they are more brittle, wear more and are harder to repair) And then, there is that elevated death rate.

OTHER COUNTRIES

The United States virtually stands alone in its fervor for fluoridation. Other countries have rejected it because of the safety issue.

The documents provided to the Mayor and City Council clearly show that each of the countries examining fluoridation rejected it because of safety. The Environmental Protection Services of the Quebec Government requested the Quebec Government to halt fluoridation because of toxic effects. The Quebec Government declared a moratorium on fluoridation in August 1977 and it is still in effect today.

The Swedish law passed in 1962 permitting fluoridation was repealed by the Swedish Parliament in 1971, because of adverse health effects.

According to Dr. J. Maurin, Director, Public Water Supply Laboratory, France has continued to reject fluoridation because of doubts of safety.

Germany discontinued fluoridation in 1971 for health and legal reasons. The safety factor has never been swept under the carpet in other countries because they didn't back themselves into a corner by saying it was safe before it was tested. The U.S. Public Health Service has made this mistake and is able to suppress safety studies because the U.S. P.H.S. controls most research funds.

CONCLUSION

We have learned the hard way, but our requirements for proof of safety are more sophisticated today. When the big push for fluoridation began in 1945, the proponents were blind to the far reaching effects of this poisonous waste material from industry. They thought they had solved two problems waste disposal and tooth decay. At that time penicillin was a new wonder drug and environmental cancer or thalidomide were unheard of. Mass experimentation was thought to be for everyone's benefit what if a few were harmed? It was not too uncommon to expose soldiers to nuclear radiation or to drop zinc cadmiumphosphide or other phosphorescent compounds on the Eastern Shore to test chemical warfare techniques. Red dye #2 and cyclamate were considered safe, and it was alright to store toxic chemicals in dumps that allow leaching into water supplies, or even to build houses on coveted chemical dumps. At that time, no one would ever have guessed that asbestos caused lung cancer or that using a tampon could increase the risk to a disease to be called Toxic Shock Syndrome. Few suspected that the Swine Flu vaccine would cause Guillain-Barre Syndrome. Nor would many suspect that 13,000 patients would die yearly from adverse reactions to prescribed drugs.

In 1980, we know better. And we do know that fluoridation has adverse effects on many. Some will have allergies and symptoms easily traceable to fluoride, others will have aches and pains thought to be arthritis, but really due to bone damage caused by fluoride. Some will have kidney and thyroid trouble and never know the cause. Still others may have premature death due to cancer from forced fluoridation... but all will have increased health risks.

Any new efforts at fluoridation must be looked at in terms of safety requirements for 1980, just as a new building must meet 1980 fire codes, because previous codes have been found to be inadequate.

I would speculate that courts of law may consider it negligent to contaminate public water supplies at this time in light of the new evidence showing adverse health effects. The promoters, 'still proclaiming that "there is no safety question," have to be accountable, legally and morally, for the illness and discomfort that may be inflicted on the population.

Yes, we all want children to have good teeth, but children are more than teeth. They are also kidneys, livers, bones, spleens and thyroids which are damaged by water contaminated with 1 ppm fluoride the level used in fluoridation. What effect will this lifetime of damage have on the quality of their lives?

If someone isn't "impressed" with this hard scientific data obtained by experts in their field, then let them have fluoridated water they can make it in their homes by adding a tenth-gram of Dro rat poison to 5 gallons of water, or they can take fluoride tablets. But let the rest have our pure, unadulterated drinking water.

Sincerely,
Richard A. Passwater, Ph.D.

Watch Online

Watch on Amazon Video Watch on iTunes

Watch on DVD

Get the Book

Rethinking Cancer, by Ruth Sackman, is an excellent companion book to the film. Learn More

Newsletter signup

Bookmark and Share